MAGEF1

Across TCGA patient cohorts, MAGEF1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEF1-associated genes across cancer lineages are Syk and cIAP. Each is linked with MAGEF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEF1-to-partner and partner-to-MAGEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Syk grouped by MAGEF1-low versus MAGEF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEF1→partner) and Y-score (partner→MAGEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Syk →	+0.469	+2.820	.041	.036	1	1
UCEC	cIAP →	+0.199	+2.833	.018	.035	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Syk by MAGEF1 expression — UCEC

Explore this box plot interactively →