MAGEF1

Across TCGA cell cohorts, MAGEF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,843 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MAGEF1-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Protein sumoylation, and DNA repair-dependent chromatin remodeling. Each is linked with MAGEF1 in more than 12 cancer types. Because this analysis shows association rather than direction, both MAGEF1-to-partner and partner-to-MAGEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of DNA-templated transcription, elongation grouped by MAGEF1-low versus MAGEF1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEF1→partner) and Y-score (partner→MAGEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of DNA-templated transcription, elongation →	+0.125	+1.260	<.001	<.001	3	13
LUNG_SCLC	Protein sumoylation →	+0.070	+0.750	<.001	<.001	3	12
LUNG_NSCLC_LUSC	DNA repair-dependent chromatin remodeling →	+0.092	+1.441	.002	<.001	3	12
OVARY	Maintenance of centrosome location →	+0.129	+1.038	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of monoatomic ion transport →	-0.110	-1.311	.002	.006	3	12
BONE	Nucleic acid transport →	+0.090	+0.638	.009	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,843 associations by consensus.

Negative regulation of DNA-templated transcription, elongation by MAGEF1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →