MAGEF1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MAGEF1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MAGEF1-associated genes across cancer lineages are SSX7 and RBMY1B. Each is linked with MAGEF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEF1-to-partner and partner-to-MAGEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSX7 grouped by MAGEF1-low versus MAGEF1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEF1→partner) and Y-score (partner→MAGEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHSSX7 →+0.433+5.285<.001.00331
SKINRBMY1B →+1.113+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SSX7 by MAGEF1 expression — STOMACH

Box plot of SSX7 in MAGEF1-low vs MAGEF1-high samples in STOMACH.

Explore this box plot interactively →

Exploration