Across TCGA patient cohorts, MAGEE2 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEE2-associated genes across cancer lineages are Caspase-7-cleavedD198, Cyclin-E2, and ERK2. Each is linked with MAGEE2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAGEE2-to-partner and partner-to-MAGEE2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEE2→partner) and Y-score (partner→MAGEE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.075	+3.178	.005	.010	3	4
UCEC	Cyclin-E2 →	+0.120	+1.372	.017	.022	3	3
UCEC	ERK2 →	+0.148	+1.662	.010	.010	3	2
UCEC	FoxM1 →	+0.196	+1.584	.011	.002	3	2
UCEC	HER2_pY1248 →	-0.170	-2.321	.033	<.001	3	2
UCEC	MEK1 →	+0.392	+1.807	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

MAGEE2 survival (RNA) · tumor vs normal (RNA) · all MAGEE2 data types