Across TCGA cell cohorts, MAGEE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 742 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MAGEE2-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of proteasomal protein catabolic process. Each is linked with MAGEE2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAGEE2-to-partner and partner-to-MAGEE2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEE2→partner) and Y-score (partner→MAGEE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.070	+0.381	<.001	.002	3	5
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.083	+0.506	.004	.003	3	5
LUNG_SCLC	Regulation of proteasomal protein catabolic process →	+0.032	+0.367	.009	.003	3	5
LUNG_SCLC	Protein K48-linked ubiquitination →	+0.034	+0.352	.004	.005	3	4
LUNG_SCLC	Establishment of RNA localization →	+0.075	+0.473	<.001	.001	3	4
SKIN	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction →	-0.036	-0.031	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

Exploration

MAGEE2 survival (RNA) · tumor vs normal (RNA) · all MAGEE2 data types