Across TCGA patient cohorts, MAGEE1 mutation is significantly associated with the RNA expression of many other genes, with 4,730 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEE1-associated genes across cancer lineages are PTMAP4, SH3BGRL3, and ANTXR2. Each is linked with MAGEE1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAGEE1-to-partner and partner-to-MAGEE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEE1→partner) and Y-score (partner→MAGEE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PTMAP4 →	+1.079	+2.341	.001	.003	3	4
UCEC	SH3BGRL3 →	+0.299	+2.169	<.001	.002	3	4
LUSC	ANTXR2 →	+0.610	+2.011	.003	.005	3	4
UCEC	BRI3BP →	+0.671	+1.970	<.001	<.001	3	3
COAD	SYCE3 →	+0.564	+2.817	<.001	.001	3	3
COAD	CCNG1P1 →	+0.110	+2.543	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,730 associations by consensus.

Exploration

MAGEE1 survival (RNA) · tumor vs normal (RNA) · all MAGEE1 data types