Across TCGA patient cohorts, MAGEE1 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEE1-associated genes across cancer lineages are Shc_pY317, S6_pS240_S244, and ASNS. Each is linked with MAGEE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAGEE1-to-partner and partner-to-MAGEE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEE1→partner) and Y-score (partner→MAGEE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.224	-1.736	<.001	<.001	3	5
UCEC	S6_pS240_S244 →	+0.289	+0.999	.013	.042	3	3
UCEC	ASNS →	+0.331	+1.280	.001	.049	3	3
UCEC	Caspase-7-cleavedD198 →	+0.561	+1.514	<.001	.012	3	3
LUSC	eIF4E →	+0.175	+2.821	.014	.035	3	2
LUSC	PR →	+0.131	+3.000	.028	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

MAGEE1 survival (RNA) · tumor vs normal (RNA) · all MAGEE1 data types