Across TCGA cell cohorts, MAGEE1 mutation is significantly associated with the RNA expression of many other genes, with 261 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAGEE1-associated genes across cancer lineages are GJA8, C1QBP, and SCO1. Each is linked with MAGEE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEE1-to-partner and partner-to-MAGEE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEE1→partner) and Y-score (partner→MAGEE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GJA8 →	+0.594	+3.734	<.001	.006	3	2
LARGE_INTESTINE	C1QBP →	+0.595	+2.005	.003	.008	3	2
LARGE_INTESTINE	SCO1 →	+0.598	+2.158	<.001	.004	3	2
LARGE_INTESTINE	ELP3 →	+0.559	+2.850	.003	<.001	3	2
LARGE_INTESTINE	POMGNT2 →	+0.783	+3.321	<.001	.003	3	2
LARGE_INTESTINE	BORCS5 →	+0.534	+3.321	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 261 associations by consensus.

Exploration

MAGEE1 survival (RNA) · tumor vs normal (RNA) · all MAGEE1 data types