MAGED2

Across TCGA patient cohorts, MAGED2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,303 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MAGED2-associated genes across cancer lineages are ADGRB2, TESMIN, and TRIM7. Each is linked with MAGED2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAGED2-to-partner and partner-to-MAGED2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAGED2 versus ADGRB2 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGED2→partner) and Y-score (partner→MAGED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADGRB2 →	+1.336	+0.507	<.001	.001	3	5
BRCA	TESMIN →	+0.929	+0.485	<.001	<.001	3	5
COAD	TRIM7 →	-1.292	-0.326	<.001	<.001	3	5
LSCC	DUSP15 →	+0.646	+0.566	<.001	<.001	3	5
HNSC	MINAR1 →	+0.477	+0.253	.001	<.001	3	5
COAD	PHF8 →	+1.098	+0.379	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,303 associations by consensus.

MAGED2 vs ADGRB2 — BRCA

Explore this scatter interactively →