MAGED2

Across TCGA cell cohorts, MAGED2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,114 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MAGED2-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Golgi vesicle transport, and Vesicle budding from membrane. Each is linked with MAGED2 in more than 18 cancer types. Because this analysis shows association rather than direction, both MAGED2-to-partner and partner-to-MAGED2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by MAGED2-low versus MAGED2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGED2→partner) and Y-score (partner→MAGED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.135	+1.376	<.001	.005	3	19
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.060	+0.925	<.001	<.001	3	15
SOFT_TISSUE	Vesicle budding from membrane →	+0.070	+1.004	<.001	<.001	3	15
OESOPHAGUS	COPII-coated vesicle budding →	+0.116	+1.406	<.001	.002	1	16
LUNG_NSCLC_LUSC	Macroautophagy →	+0.066	+1.571	.007	<.001	3	13
OESOPHAGUS	Regulation of macroautophagy →	+0.082	+1.491	.002	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,114 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by MAGED2 expression — OESOPHAGUS

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