MAGEC3

Across TCGA patient cohorts, MAGEC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,979 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible MAGEC3-associated GO terms across cancer lineages are Peptidyl-lysine modification, Regulation of DNA-templated transcription elongation, and Protein stabilization. Each is linked with MAGEC3 in more than 23 cancer types. Because this analysis shows association rather than direction, both MAGEC3-to-partner and partner-to-MAGEC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by MAGEC3-low versus MAGEC3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEC3→partner) and Y-score (partner→MAGEC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Peptidyl-lysine modification →	+0.063	+0.074	<.001	<.001	3	24
STAD	Regulation of DNA-templated transcription elongation →	+0.073	+0.076	<.001	<.001	3	23
STAD	Protein stabilization →	+0.068	+0.086	<.001	<.001	3	23
STAD	Nucleoside phosphate biosynthetic process →	+0.079	+0.104	<.001	<.001	3	23
STAD	Macromolecule methylation →	+0.063	+0.087	<.001	<.001	3	23
SCLC	Obsolete histone modification →	+0.108	+0.748	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,979 associations by consensus.

Peptidyl-lysine modification by MAGEC3 expression — STAD

Explore this box plot interactively →