MAGEC2

Across TCGA patient cohorts, MAGEC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,347 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MAGEC2-associated GO terms across cancer lineages are Metaphase chromosome alignment, Positive regulation of mitotic sister chromatid separation, and Protein localization to condensed chromosome. Each is linked with MAGEC2 in more than 13 cancer types. Because this analysis shows association rather than direction, both MAGEC2-to-partner and partner-to-MAGEC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase chromosome alignment grouped by MAGEC2-low versus MAGEC2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEC2→partner) and Y-score (partner→MAGEC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Metaphase chromosome alignment →	+0.052	+0.745	<.001	<.001	3	14
STAD	Positive regulation of mitotic sister chromatid separation →	+0.059	+0.804	<.001	<.001	3	13
STAD	Protein localization to condensed chromosome →	+0.048	+0.653	<.001	<.001	3	13
STAD	Mitotic sister chromatid separation →	+0.049	+0.781	<.001	<.001	3	13
ESCA	Telomerase RNA localization →	+0.042	+0.625	.001	.005	3	12
STAD	Meiotic spindle organization →	+0.053	+0.773	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,347 associations by consensus.

Metaphase chromosome alignment by MAGEC2 expression — STAD

Explore this box plot interactively →