MAGEC1

Across TCGA patient cohorts, MAGEC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,078 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MAGEC1-associated GO terms across cancer lineages are Attachment of spindle microtubules to kinetochore, Positive regulation of mitotic cell cycle, and Anaphase-promoting complex-dependent catabolic process. Each is linked with MAGEC1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MAGEC1-to-partner and partner-to-MAGEC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Attachment of spindle microtubules to kinetochore grouped by MAGEC1-low versus MAGEC1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEC1→partner) and Y-score (partner→MAGEC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Attachment of spindle microtubules to kinetochore →	+0.055	+0.408	<.001	<.001	3	12
STAD	Positive regulation of mitotic cell cycle →	+0.046	+0.395	<.001	.001	3	12
TGCT	Anaphase-promoting complex-dependent catabolic process →	+0.051	+1.698	<.001	<.001	3	11
ESCA	Regulation of attachment of spindle microtubules to kinetochore →	+0.058	+1.109	.001	<.001	2	12
STAD	Positive regulation of mitotic sister chromatid separation →	+0.063	+0.430	<.001	<.001	3	11
ESCA	DNA replication initiation →	+0.064	+1.004	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,078 associations by consensus.

Attachment of spindle microtubules to kinetochore by MAGEC1 expression — STAD

Explore this box plot interactively →