MAGEB6B

Across TCGA patient cohorts, MAGEB6B mutation is significantly associated with the RNA expression of many other genes, with 3,024 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MAGEB6B-associated genes across cancer lineages are LRRC59, CCT5, and PDCD5. Each is linked with MAGEB6B in more than 3 cancer types. Because this analysis shows association rather than direction, both MAGEB6B-to-partner and partner-to-MAGEB6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRRC59 grouped by MAGEB6B-low versus MAGEB6B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB6B→partner) and Y-score (partner→MAGEB6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRRC59 →	+0.507	+2.502	.001	.009	3	4
LUSC	CCT5 →	+0.412	+2.087	.008	.006	3	4
BLCA	PDCD5 →	+0.665	+3.220	<.001	.009	3	4
LIHC	RPS2P39 →	+0.043	+4.293	<.001	.009	3	3
HNSC	ARL16 →	+0.571	+2.842	.001	.001	3	3
SKCM	CORO2B →	-1.126	-2.396	.006	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,024 associations by consensus.

LRRC59 by MAGEB6B expression — UCEC

Explore this box plot interactively →