MAGEB6B

Across TCGA patient cohorts, MAGEB6B mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEB6B-associated genes across cancer lineages are Di-Ras3, Smad4, and Caveolin-1. Each is linked with MAGEB6B in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGEB6B-to-partner and partner-to-MAGEB6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Di-Ras3 grouped by MAGEB6B-low versus MAGEB6B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB6B→partner) and Y-score (partner→MAGEB6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Di-Ras3 →	-0.157	-2.446	.005	.018	3	3
LUSC	Smad4 →	+0.100	+2.825	.027	.033	3	2
LUSC	Caveolin-1 →	-0.554	-2.450	.048	.019	3	2
UCEC	EGFR_pY1173 →	+0.078	+2.999	.010	.035	3	2
UCEC	eIF4E →	+0.205	+2.087	.011	.005	3	2
UCEC	Notch1 →	+0.167	+3.598	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Di-Ras3 by MAGEB6B expression — UCEC

Explore this box plot interactively →