MAGEB6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAGEB6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,049 significant associations in total. THYM shows the largest number of these associations.

The most reproducible MAGEB6-associated GO terms across cancer lineages are Positive regulation of establishment of protein localization to telomere, Female meiosis chromosome segregation, and DNA replication initiation. Each is linked with MAGEB6 in more than 15 cancer types. Because this analysis shows association rather than direction, both MAGEB6-to-partner and partner-to-MAGEB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of establishment of protein localization to telomere grouped by MAGEB6-low versus MAGEB6-high in KIRP.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB6→partner) and Y-score (partner→MAGEB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPPositive regulation of establishment of protein localization to telomere →+0.077+0.040<.001.005316
LUADFemale meiosis chromosome segregation →+0.087+0.081<.001<.001314
TGCTDNA replication initiation →+0.062+0.736<.001<.001215
STADPositive regulation of telomerase RNA localization to Cajal body →+0.073+0.091<.001<.001313
STADDNA strand elongation →+0.060+0.106<.001<.001313
STADPositive regulation of cytokinesis →+0.067+0.131<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,049 associations by consensus.

Positive regulation of establishment of protein localization to telomere by MAGEB6 expression — KIRP

Box plot of Positive regulation of establishment of protein localization to telomere in MAGEB6-low vs MAGEB6-high samples in KIRP.

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