MAGEB6

Across TCGA patient cohorts, MAGEB6 mutation is significantly associated with the RNA expression of many other genes, with 3,922 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEB6-associated genes across cancer lineages are CORO2B, SNW1, and HPRT1. Each is linked with MAGEB6 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAGEB6-to-partner and partner-to-MAGEB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CORO2B grouped by MAGEB6-low versus MAGEB6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB6→partner) and Y-score (partner→MAGEB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CORO2B →	-0.432	-2.000	.004	<.001	3	4
LUSC	SNW1 →	+0.232	+1.921	.009	.001	3	4
SKCM	HPRT1 →	+0.352	+1.153	.004	.007	3	3
LUAD	PATL1 →	+0.381	+2.807	.004	.003	3	3
UCEC	IL17RA →	+0.274	+1.457	.002	.002	3	3
SKCM	GAS2L1 →	+0.418	+1.434	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,922 associations by consensus.

CORO2B by MAGEB6 expression — UCEC

Explore this box plot interactively →