MAGEB3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAGEB3 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEB3-associated genes across cancer lineages are FoxM1, ACC1, and Notch1. Each is linked with MAGEB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEB3-to-partner and partner-to-MAGEB3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB3→partner) and Y-score (partner→MAGEB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFoxM1 →+0.308+2.523<.001<.00132
UCECACC1 →+0.319+1.887.009.02932
UCECNotch1 →+0.182+2.137<.001.00132
UCECASNS →+0.399+1.584.001.03432
UCECBak →+0.295+2.523<.001<.00132
UCECc-Met →-0.208-2.137.041.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration