Across TCGA patient cohorts, MAGEA6 mutation is significantly associated with the RNA expression of many other genes, with 1,565 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEA6-associated genes across cancer lineages are MIR6894, MICU1, and WNT6. Each is linked with MAGEA6 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGEA6-to-partner and partner-to-MAGEA6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA6→partner) and Y-score (partner→MAGEA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR6894 →	+0.519	+3.453	<.001	.009	3	3
SKCM	MICU1 →	+0.348	+2.294	.002	<.001	3	2
SKCM	WNT6 →	-0.412	-2.150	.009	.003	3	2
SKCM	ACAT2 →	+0.741	+3.198	<.001	<.001	3	2
UCEC	ZWINT →	+0.864	+2.540	.001	.009	3	2
SKCM	STIL →	+0.487	+1.995	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,565 associations by consensus.

Exploration

MAGEA6 survival (RNA) · tumor vs normal (RNA) · all MAGEA6 data types