Across TCGA cell cohorts, MAGEA6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MAGEA6-associated genes across cancer lineages are MT4, OR4X2, and DRD3. Each is linked with MAGEA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA6-to-partner and partner-to-MAGEA6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA6→partner) and Y-score (partner→MAGEA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MT4 →	+0.222	+5.321	<.001	.005	3	1
CNS	OR4X2 →	+0.034	+4.981	<.001	.008	3	1
LARGE_INTESTINE	DRD3 →	+0.012	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

MAGEA6 survival (RNA) · tumor vs normal (RNA) · all MAGEA6 data types