MAGEA5

Across TCGA patient cohorts, MAGEA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,930 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MAGEA5-associated GO terms across cancer lineages are Telomere maintenance, Telomere organization, and Positive regulation of cell cycle process. Each is linked with MAGEA5 in more than 20 cancer types. Because this analysis shows association rather than direction, both MAGEA5-to-partner and partner-to-MAGEA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance grouped by MAGEA5-low versus MAGEA5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA5→partner) and Y-score (partner→MAGEA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance →	+0.047	+0.056	<.001	<.001	3	20
STAD	Telomere organization →	+0.043	+0.058	<.001	<.001	2	21
STAD	Positive regulation of cell cycle process →	+0.045	+0.053	<.001	<.001	3	19
STAD	Positive regulation of DNA metabolic process →	+0.047	+0.071	<.001	.001	3	19
STAD	Metaphase chromosome alignment →	+0.059	+0.055	<.001	<.001	3	19
CHOL	Cellular response to UV →	+0.044	+0.243	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,930 associations by consensus.

Telomere maintenance by MAGEA5 expression — STAD

Explore this box plot interactively →