Across TCGA patient cohorts, MAGEA11 mutation is significantly associated with the RNA expression of many other genes, with 3,214 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEA11-associated genes across cancer lineages are MIR8053, RNU4-6P, and CD1A. Each is linked with MAGEA11 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGEA11-to-partner and partner-to-MAGEA11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA11→partner) and Y-score (partner→MAGEA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR8053 →	+0.394	+5.136	<.001	.002	3	3
BRCA	RNU4-6P →	+0.437	+5.540	.007	.004	3	3
LUAD	CD1A →	-1.590	-2.807	<.001	.003	3	3
UCEC	LRR1 →	+0.468	+2.021	.002	.005	3	3
UCEC	CDT1 →	+0.857	+2.091	<.001	<.001	3	3
UCEC	CHAF1A →	+0.661	+2.399	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,214 associations by consensus.

Exploration

MAGEA11 survival (RNA) · tumor vs normal (RNA) · all MAGEA11 data types