MAGEA11

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAGEA11 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEA11-associated genes across cancer lineages are MEK1, MAPK_pT202_Y204, and p38-MAPK_pT180_Y182. Each is linked with MAGEA11 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGEA11-to-partner and partner-to-MAGEA11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA11→partner) and Y-score (partner→MAGEA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEK1 →+0.461+2.502<.001.00133
LUADMAPK_pT202_Y204 →-0.623-3.459<.001.00532
LUADp38-MAPK_pT180_Y182 →-0.641-3.000<.001.03432
UCEC4E-BP1 →+0.307+1.837.001.01432
UCECEGFR_pY1068 →-0.271-2.392.002<.00132
UCECJNK_pT183_Y185 →-0.218-2.906<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration