Across TCGA cell cohorts, MAGEA11 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAGEA11-associated genes across cancer lineages are SERPINA12, ZP2, and MAGEB4. Each is linked with MAGEA11 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA11-to-partner and partner-to-MAGEA11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA11→partner) and Y-score (partner→MAGEA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SERPINA12 →	+0.028	+4.544	<.001	.003	3	2
BLOOD_Leukemia	ZP2 →	+0.179	+4.409	<.001	.005	3	1
BLOOD_Leukemia	MAGEB4 →	+0.046	+4.705	<.001	.003	3	1
BLOOD_Leukemia	ZIC3 →	+0.019	+5.060	<.001	.001	3	1
BLOOD_Leukemia	OR10A3 →	+0.033	+4.539	<.001	.007	3	1
BLOOD_Leukemia	KRTAP17-1 →	+0.695	+5.060	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

MAGEA11 survival (RNA) · tumor vs normal (RNA) · all MAGEA11 data types