Across TCGA pan-cancer cohorts, MAFK mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MAFK data layer compared with 24 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MAFK mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MAFK expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

PDAC, GBM, and LUAD are the cancer types where MAFK mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	II,III,IV	1.000	0.120	.017	14	view →
GBM	OS	Median	All	0.217	0.796	.006	12	view →
LUAD	OS	Tertile	II,III,IV	0.619	0.927	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MAFK tumor-vs-normal RNA expression · all MAFK data types