Across TCGA patient cohorts, MAFG mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MAFG-associated genes across cancer lineages are MED15P7, E2F6P1, and RN7SL578P. Each is linked with MAFG in more than 1 cancer types. Because this analysis shows association rather than direction, both MAFG-to-partner and partner-to-MAFG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFG→partner) and Y-score (partner→MAFG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MED15P7 →	+0.092	+5.867	<.001	.003	3	1
SKCM	E2F6P1 →	+0.066	+5.594	<.001	.004	3	1
SKCM	RN7SL578P →	+0.181	+5.594	<.001	.004	3	1
SKCM	RN7SL91P →	+0.168	+5.771	<.001	.003	3	1
SKCM	RN7SL709P →	+0.157	+5.224	<.001	.007	3	1
SKCM	RN7SL643P →	+0.173	+6.993	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

MAFG survival (RNA) · tumor vs normal (RNA) · all MAFG data types