Across TCGA patient cohorts, MAFB protein abundance is significantly associated with the RNA expression of many other genes, with 7,510 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAFB-associated genes across cancer lineages are CLEC2B, FCER1G, and IFI16. Each is linked with MAFB in more than 3 cancer types. Because this analysis shows association rather than direction, both MAFB-to-partner and partner-to-MAFB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFB→partner) and Y-score (partner→MAFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CLEC2B →	+0.757	+0.577	<.001	<.001	3	4
GBM	FCER1G →	+0.876	+0.576	<.001	<.001	3	4
GBM	IFI16 →	+0.815	+0.725	<.001	<.001	3	4
GBM	LAIR1 →	+1.092	+0.650	<.001	<.001	3	4
LSCC	CLEC7A →	+1.095	+0.561	<.001	.002	3	4
LUAD	MSR1 →	+1.142	+0.536	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,510 associations by consensus.

Exploration

MAFB survival (RNA) · tumor vs normal (RNA) · all MAFB data types