MAFB

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAFB mutation is significantly associated with the RNA expression of many other genes, with 3,331 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAFB-associated genes across cancer lineages are RNU6-1124P, RNA5SP436, and PSAT1P2. Each is linked with MAFB in more than 1 cancer types. Because this analysis shows association rather than direction, both MAFB-to-partner and partner-to-MAFB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFB→partner) and Y-score (partner→MAFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-1124P →+0.237+7.741<.001.00932
COADRNA5SP436 →+0.574+7.741<.001.00932
LUADPSAT1P2 →+0.335+4.990<.001.00932
HNSCPSAT1P4 →+0.133+4.245<.001.00832
UCECRNU6-358P →+0.265+2.285.001.00532
SKCMRNU6-104P →+0.350+6.469<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,331 associations by consensus.

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