Across TCGA cell cohorts, MAFB mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAFB-associated genes across cancer lineages are C2orf42, GALR3, and GABRG1. Each is linked with MAFB in more than 1 cancer types. Because this analysis shows association rather than direction, both MAFB-to-partner and partner-to-MAFB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFB→partner) and Y-score (partner→MAFB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C2orf42 →	+0.627	+3.215	<.001	.009	3	1
LARGE_INTESTINE	GALR3 →	+0.087	+3.424	.002	.006	3	1
LARGE_INTESTINE	GABRG1 →	+0.007	+2.518	.006	.006	3	1
LARGE_INTESTINE	OR52H1 →	+0.024	+2.669	<.001	.004	3	1
LARGE_INTESTINE	TRARG1 →	+0.016	+3.023	.001	.002	3	1
CNS	IL21 →	+0.025	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

MAFB survival (RNA) · tumor vs normal (RNA) · all MAFB data types