Across TCGA cell cohorts, MAFA protein abundance is significantly associated with the RNA expression of many other genes, with 1,186 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible MAFA-associated genes across cancer lineages are CIAO2A, MDP1, and MICALL2. Each is linked with MAFA in more than 3 cancer types. Because this analysis shows association rather than direction, both MAFA-to-partner and partner-to-MAFA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAFA→partner) and Y-score (partner→MAFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CIAO2A →	-1.111	-1.545	.002	.004	3	4
BREAST	MDP1 →	+0.912	+1.505	.003	<.001	3	4
BLOOD_Leukemia	MICALL2 →	-1.951	-1.135	.003	.004	3	4
LUNG_SCLC	MYL6B →	+0.861	+1.259	.006	.003	3	3
LUNG_SCLC	C1QL1 →	+2.136	+1.412	.002	.001	3	3
LUNG_SCLC	SGF29 →	+0.604	+1.130	.003	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,186 associations by consensus.

Exploration

MAFA survival (RNA) · tumor vs normal (RNA) · all MAFA data types