MAF1

Across TCGA cell cohorts, MAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,484 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MAF1-associated GO terms across cancer lineages are miRNA-mediated gene silencing by mRNA destabilization, Central nervous system morphogenesis, and Cellular response to salt. Each is linked with MAF1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MAF1-to-partner and partner-to-MAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, miRNA-mediated gene silencing by mRNA destabilization grouped by MAF1-low versus MAF1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAF1→partner) and Y-score (partner→MAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	miRNA-mediated gene silencing by mRNA destabilization →	+0.133	+1.034	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Central nervous system morphogenesis →	-0.266	-0.879	<.001	<.001	3	10
BONE	Cellular response to salt →	+0.161	+0.955	.003	<.001	3	9
LUNG_NSCLC_LUAD	Response to sodium arsenite →	+0.133	+0.609	.001	.004	3	9
LIVER	Cellular response to sodium arsenite →	+0.184	+0.659	<.001	<.001	3	8
SKIN	Spermidine transmembrane transport →	+0.591	+0.585	.006	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,484 associations by consensus.

miRNA-mediated gene silencing by mRNA destabilization by MAF1 expression — OVARY

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