MAF

Across TCGA patient cohorts, MAF RNA expression is significantly associated with the protein abundance of many other proteins, with 18,695 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MAF-associated proteins across cancer lineages are PPM1F, COPZ2, and PLXDC2. Each is linked with MAF in more than 8 cancer types. Because this analysis shows association rather than direction, both MAF-to-partner and partner-to-MAF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAF versus PPM1F in UCEC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAF→partner) and Y-score (partner→MAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPM1F →	+0.440	+1.009	<.001	<.001	3	9
OV	COPZ2 →	+0.867	+0.714	<.001	.002	3	8
BRCA	PLXDC2 →	+0.527	+0.545	<.001	<.001	3	8
BRCA	IKBIP →	+0.532	+0.858	<.001	<.001	3	8
UCEC	ILK →	+0.637	+0.926	<.001	<.001	3	8
COAD	LGALS1 →	+0.654	+0.765	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,695 associations by consensus.

MAF vs PPM1F — UCEC

Explore this scatter interactively →