MAF

Across TCGA cell cohorts, MAF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,118 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAF-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Negative regulation of syncytium formation by plasma membrane fusion, and Golgi vesicle transport. Each is linked with MAF in more than 10 cancer types. Because this analysis shows association rather than direction, both MAF-to-partner and partner-to-MAF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by MAF-low versus MAF-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAF→partner) and Y-score (partner→MAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.065	+0.616	<.001	.002	3	11
LUNG_NSCLC_LUSC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.094	+0.915	<.001	.009	3	11
BONE	Golgi vesicle transport →	+0.078	+1.710	<.001	<.001	3	11
LUNG_SCLC	Regulation of myoblast fusion →	+0.090	+1.779	<.001	<.001	3	11
LUNG_SCLC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.098	+2.200	<.001	<.001	3	10
CNS	Aerobic respiration →	+0.058	+1.236	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,118 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by MAF expression — PANCREAS

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