MAEA

Across TCGA patient cohorts, MAEA protein abundance is significantly associated with the RNA expression of many other genes, with 9,132 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAEA-associated genes across cancer lineages are RABIF, S100B, and JAML. Each is linked with MAEA in more than 3 cancer types. Because this analysis shows association rather than direction, both MAEA-to-partner and partner-to-MAEA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAEA versus RABIF in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAEA→partner) and Y-score (partner→MAEA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RABIF →	+0.381	+0.140	.009	.004	3	4
HNSC	S100B →	-0.775	-0.145	.004	.005	3	4
HNSC	JAML →	-0.710	-0.128	.001	.008	3	4
LSCC	GMPS →	+0.800	+0.221	<.001	<.001	3	4
BRCA	CENPN →	+0.632	+0.177	.001	.001	3	4
HNSC	RNF187 →	+0.577	+0.211	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,132 associations by consensus.

MAEA vs RABIF — HNSC

Explore this scatter interactively →