MACROD1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MACROD1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,033 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MACROD1-associated genes across cancer lineages are MEDAG, COL5A2, and LINC01614. Each is linked with MACROD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MACROD1-to-partner and partner-to-MACROD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MACROD1 versus MEDAG in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MACROD1→partner) and Y-score (partner→MACROD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMEDAG →-1.591-0.439<.001.00235
OVCOL5A2 →-1.952-0.492<.001<.00135
OVLINC01614 →-2.756-0.497<.001<.00135
OVDOK3 →-0.997-0.549<.001.00135
OVADAM12 →-1.905-0.592<.001<.00135
OVIKBIP →-0.897-0.668<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,033 associations by consensus.

MACROD1 vs MEDAG — OV

Per-sample scatter of MACROD1 vs MEDAG in OV (Pearson r = -0.39).

Explore this scatter interactively →

Exploration