MACF1

Across TCGA patient cohorts, MACF1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,379 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MACF1-associated genes across cancer lineages are ERRFI1, CRABP2, and HSPE1P8. Each is linked with MACF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MACF1-to-partner and partner-to-MACF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MACF1 versus ERRFI1 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MACF1→partner) and Y-score (partner→MACF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERRFI1 →	+1.273	+0.299	<.001	<.001	3	5
UCEC	CRABP2 →	+1.321	+0.207	.001	.004	3	5
UCEC	HSPE1P8 →	+1.041	+0.256	.002	.001	3	5
UCEC	RNA5SP44 →	+1.615	+0.366	<.001	<.001	3	5
UCEC	SMIM3 →	+0.874	+0.234	<.001	.001	3	5
UCEC	TNC →	+1.095	+0.187	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,379 associations by consensus.

MACF1 vs ERRFI1 — UCEC

Explore this scatter interactively →