Across TCGA patient cohorts, MACC1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,918 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MACC1-associated genes across cancer lineages are MACC1-AS1, TACSTD2, and CLDN4. Each is linked with MACC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MACC1-to-partner and partner-to-MACC1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MACC1→partner) and Y-score (partner→MACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MACC1-AS1 →	+1.846	+0.955	<.001	<.001	3	7
COAD	TACSTD2 →	+2.046	+0.626	.002	.003	3	6
CCRCC	CLDN4 →	+1.333	+0.603	<.001	<.001	3	5
LSCC	KRT80 →	+1.504	+0.434	<.001	<.001	3	5
OV	GIPC1 →	+0.496	+0.491	.002	.002	3	4
LSCC	PTK6 →	+1.194	+0.419	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,918 associations by consensus.

Exploration

MACC1 survival (RNA) · tumor vs normal (RNA) · all MACC1 data types