Across TCGA cell cohorts, MACC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,299 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MACC1-associated GO terms across cancer lineages are Vestibulocochlear nerve formation, Positive regulation of sodium ion transport, and Maintenance of blood-brain barrier. Each is linked with MACC1 in more than 12 cancer types. Because this analysis shows association rather than direction, both MACC1-to-partner and partner-to-MACC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MACC1→partner) and Y-score (partner→MACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Vestibulocochlear nerve formation →	+1.103	+1.588	<.001	<.001	3	13
URINARY_TRACT	Positive regulation of sodium ion transport →	+0.204	+2.186	<.001	.003	3	12
LUNG_NSCLC_LUSC	Maintenance of blood-brain barrier →	+0.173	+2.465	.001	<.001	3	12
OESOPHAGUS	Sensory perception of salty taste →	+1.651	+2.906	<.001	<.001	3	12
BREAST	Positive regulation of blood-brain barrier permeability →	+0.348	+1.772	.001	<.001	3	12
LUNG_NSCLC_LUSC	Renal vesicle formation →	-1.416	-3.178	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,299 associations by consensus.

Exploration

MACC1 survival (RNA) · tumor vs normal (RNA) · all MACC1 data types