Across TCGA cell cohorts, MACC1 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,280 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MACC1-associated GO terms across cancer lineages are Regulation of vasculature development, Gastrulation, and Regulation of angiogenesis. Each is linked with MACC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MACC1-to-partner and partner-to-MACC1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MACC1→partner) and Y-score (partner→MACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of vasculature development →	+0.059	+1.272	<.001	.004	3	5
LIVER	Gastrulation →	+0.103	+1.375	.007	.001	3	5
LUNG_NSCLC_LUAD	Regulation of angiogenesis →	+0.056	+1.076	.004	.004	3	5
LUNG_NSCLC_LUAD	Regulation of transforming growth factor beta receptor signaling pathway →	+0.043	+0.826	.003	<.001	3	4
LUNG_NSCLC_LUAD	Regulation of cellular response to transforming growth factor beta stimulus →	+0.041	+0.781	.004	<.001	3	4
SOFT_TISSUE	Multivesicular body sorting pathway →	+0.087	+1.228	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,280 associations by consensus.

Exploration

MACC1 survival (RNA) · tumor vs normal (RNA) · all MACC1 data types