MAB21L3

Across TCGA patient cohorts, MAB21L3 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAB21L3-associated genes across cancer lineages are CD4+ Tcm, aDC, and CD8+ T-cells. Each is linked with MAB21L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAB21L3-to-partner and partner-to-MAB21L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by MAB21L3-low versus MAB21L3-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAB21L3→partner) and Y-score (partner→MAB21L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD4+ Tcm →	+0.012	+5.468	<.001	.043	3	1
UCEC	aDC →	+0.075	+2.177	.023	.035	3	1
UCEC	CD8+ T-cells →	+0.022	+2.845	<.001	.001	3	1
UCEC	Chondrocytes →	+0.005	+1.827	.045	.041	3	1
UCEC	CD4+ naive T-cells →	+0.011	+2.852	<.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CD4+ Tcm by MAB21L3 expression — HNSC

Explore this box plot interactively →