MAB21L3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MAB21L3 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MAB21L3-associated genes across cancer lineages are GDF3. Each is linked with MAB21L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAB21L3-to-partner and partner-to-MAB21L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GDF3 grouped by MAB21L3-low versus MAB21L3-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAB21L3→partner) and Y-score (partner→MAB21L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTGDF3 →+0.135+5.169<.001.00531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GDF3 by MAB21L3 expression — BREAST

Box plot of GDF3 in MAB21L3-low vs MAB21L3-high samples in BREAST.

Explore this box plot interactively →

Exploration