MAB21L1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAB21L1 protein abundance is significantly associated with the RNA expression of many other genes, with 308 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAB21L1-associated genes across cancer lineages are CRYBB1, TRMU, and HDAC10. Each is linked with MAB21L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAB21L1-to-partner and partner-to-MAB21L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAB21L1 versus CRYBB1 in GBM, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAB21L1→partner) and Y-score (partner→MAB21L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCRYBB1 →-0.494-0.580.009.00831
GBMTRMU →+0.392+0.694.002.00531
GBMHDAC10 →+0.242+0.611.001.00531
GBMRBM3 →+0.350+0.866.001.00931
GBMGML →-0.070-0.833.004.00331
GBMTNFRSF10A →-0.526-0.711.003.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 308 associations by consensus.

MAB21L1 vs CRYBB1 — GBM

Per-sample scatter of MAB21L1 vs CRYBB1 in GBM (Pearson r = -0.48).

Explore this scatter interactively →

Exploration