MAB21L1

Across TCGA cell cohorts, MAB21L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,393 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAB21L1-associated GO terms across cancer lineages are Regulation of transcription initiation by RNA polymerase II, Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage, and Positive regulation of telomere maintenance via telomerase. Each is linked with MAB21L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAB21L1-to-partner and partner-to-MAB21L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription initiation by RNA polymerase II grouped by MAB21L1-low versus MAB21L1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAB21L1→partner) and Y-score (partner→MAB21L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of transcription initiation by RNA polymerase II →	+0.066	+0.028	.009	.008	2	6
BLOOD_Lymphoma	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	+0.044	+0.548	.005	.004	3	5
BLOOD_Leukemia	Positive regulation of telomere maintenance via telomerase →	+0.039	+0.442	<.001	.007	3	5
BLOOD_Leukemia	Regulation of transepithelial transport →	+0.022	+0.462	<.001	.005	3	4
BLOOD_Leukemia	Interleukin-23-mediated signaling pathway →	+0.139	+0.697	<.001	<.001	3	4
BLOOD_Leukemia	Postsynapse to nucleus signaling pathway →	+0.064	+0.497	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,393 associations by consensus.

Regulation of transcription initiation by RNA polymerase II by MAB21L1 expression — PANCREAS

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