LZTS1-AS1

Across TCGA pan-cancer cohorts, LZTS1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated LZTS1-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LZTS1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LZTS1-AS1 expression acts as an unfavorable survival marker, although some lineages such as STAD and ESCA show a favorable association.

UCEC, DLBC, and STAD are the cancer types where LZTS1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	0.675	0.826	.006	72	view →
DLBC	OS	Tertile	All	0.732	1.000	.005	42	view →
STAD	OS	Tertile	IV	0.776	0.152	.002	37	view →
READ	DFS	Tertile	All	0.224	0.730	.009	27	view →
BLCA	DFS	Tertile	All	0.179	0.507	.012	24	view →
ESCA	OS	Quartile	III,IV	0.795	0.265	.001	24	view →
LGG	OS	Tertile	All	0.681	0.835	.001	24	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
LUSC	OS	Tertile	III,IV	0.054	0.768	<.001	18	view →
ACC	OS	Tertile	All	0.557	0.892	.003	18	view →
SKCM	OS	Quartile	III,IV	0.890	0.748	.009	14	view →
THCA	OS	Tertile	III,IV	0.873	0.970	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

LZTS1-AS1–UCEC (DFS)

Open the UCEC breakdown →