LZTR1

Across TCGA patient cohorts, LZTR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,311 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LZTR1-associated proteins across cancer lineages are TRMT2A, ZDHHC8_S526, and HSP90B1. Each is linked with LZTR1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LZTR1-to-partner and partner-to-LZTR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LZTR1 versus TRMT2A in PDAC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LZTR1→partner) and Y-score (partner→LZTR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TRMT2A →	+0.288	+0.285	<.001	<.001	3	4
OV	ZDHHC8_S526 →	+0.623	+0.427	<.001	.003	3	4
LUAD	HSP90B1 →	-0.318	-0.323	.001	<.001	3	4
GBM	MAPK1 →	+0.385	+0.382	<.001	.001	2	5
CCRCC	KANK2 →	+0.380	+0.221	<.001	.001	3	4
PDAC	PIN1 →	+0.330	+0.281	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,311 associations by consensus.

LZTR1 vs TRMT2A — PDAC

Explore this scatter interactively →