LZTR1

Across TCGA cell cohorts, LZTR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,811 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LZTR1-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Cytosolic transport. Each is linked with LZTR1 in more than 18 cancer types. Because this analysis shows association rather than direction, both LZTR1-to-partner and partner-to-LZTR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by LZTR1-low versus LZTR1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LZTR1→partner) and Y-score (partner→LZTR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.173	+1.559	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.173	+1.559	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.088	+1.693	<.001	<.001	3	16
BLOOD_Lymphoma	Negative regulation of calcium ion export across plasma membrane →	+0.062	+0.733	<.001	<.001	3	16
SKIN	Endosomal transport →	+0.064	+1.418	<.001	<.001	3	15
SKIN	Retrograde transport, endosome to Golgi →	+0.076	+1.126	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,811 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by LZTR1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →