LZTFL1

Across TCGA cell cohorts, LZTFL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,052 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LZTFL1-associated GO terms across cancer lineages are Protein localization to non-motile cilium, Negative regulation of protein localization to ciliary membrane, and Regulation of protein localization to cilium. Each is linked with LZTFL1 in more than 14 cancer types. Because this analysis shows association rather than direction, both LZTFL1-to-partner and partner-to-LZTFL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to non-motile cilium grouped by LZTFL1-low versus LZTFL1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LZTFL1→partner) and Y-score (partner→LZTFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein localization to non-motile cilium →	+0.080	+1.002	<.001	<.001	3	14
URINARY_TRACT	Negative regulation of protein localization to ciliary membrane →	+0.138	+0.837	.002	.003	2	15
LUNG_SCLC	Regulation of protein localization to cilium →	+0.100	+0.855	<.001	<.001	3	13
LUNG_SCLC	Intraciliary anterograde transport →	+0.123	+1.089	<.001	<.001	3	12
LARGE_INTESTINE	Protein localization to cilium →	+0.053	+0.717	.001	<.001	3	12
URINARY_TRACT	Adiponectin-activated signaling pathway →	+0.131	+0.986	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,052 associations by consensus.

Protein localization to non-motile cilium by LZTFL1 expression — URINARY_TRACT

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