LZIC

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LZIC RNA expression is significantly associated with the protein abundance of many other proteins, with 19,124 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LZIC-associated proteins across cancer lineages are DFFA, USP48, and DNAJC8. Each is linked with LZIC in more than 8 cancer types. Because this analysis shows association rather than direction, both LZIC-to-partner and partner-to-LZIC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LZIC versus DFFA in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LZIC→partner) and Y-score (partner→LZIC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDFFA →+0.297+0.402<.001<.00139
OVUSP48 →+0.356+0.475<.001<.00138
OVDNAJC8 →+0.307+0.383<.001.00337
OVLRRC47 →+0.299+0.373<.001<.00137
LSCCRPA2 →+0.340+0.550<.001<.00136
GBMTHEMIS2 →-0.390-0.327<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,124 associations by consensus.

LZIC vs DFFA — OV

Per-sample scatter of LZIC vs DFFA in OV (Pearson r = 0.44).

Explore this scatter interactively →

Exploration