LZIC

Across TCGA cell cohorts, LZIC RNA expression is significantly associated with the go_rna of many other GO terms, with 3,950 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LZIC-associated GO terms across cancer lineages are Response to methionine, Cellular response to methionine, and Regulation of chromosome segregation. Each is linked with LZIC in more than 12 cancer types. Because this analysis shows association rather than direction, both LZIC-to-partner and partner-to-LZIC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to methionine grouped by LZIC-low versus LZIC-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LZIC→partner) and Y-score (partner→LZIC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Response to methionine →	+0.116	+0.753	.004	.009	3	13
LUNG_SCLC	Cellular response to methionine →	+0.116	+0.753	.004	.009	3	13
OESOPHAGUS	Regulation of chromosome segregation →	+0.130	+0.644	.002	<.001	3	13
CNS	Nuclear division →	+0.059	+0.591	<.001	<.001	3	13
OESOPHAGUS	Regulation of sister chromatid segregation →	+0.131	+0.639	.001	<.001	3	13
OESOPHAGUS	Protein localization to kinetochore →	+0.142	+0.615	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,950 associations by consensus.

Response to methionine by LZIC expression — LUNG_SCLC

Explore this box plot interactively →