Across TCGA cell cohorts, LYZL6 RNA expression is significantly associated with the mutation status of many other genes, with 131 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LYZL6-associated genes across cancer lineages are PCDHB4, ARID4B, and KMT2A. Each is linked with LYZL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LYZL6-to-partner and partner-to-LYZL6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LYZL6→partner) and Y-score (partner→LYZL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PCDHB4 →	+5.369	+0.019	.004	<.001	3	2
LUNG_SCLC	ARID4B →	+4.643	+0.090	.004	<.001	3	2
LUNG_NSCLC_LUAD	KMT2A →	+2.696	+0.060	.001	.002	3	2
PANCREAS	KMT2D →	+2.652	+0.047	.007	<.001	3	1
KIDNEY	MAGI3 →	+4.954	+0.037	<.001	<.001	3	1
SOFT_TISSUE	ELF4 →	+5.369	+0.019	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 131 associations by consensus.

Exploration

LYZL6 survival (RNA) · tumor vs normal (RNA) · all LYZL6 data types